Investing in African health systems is an opportunity to drive economic development and growth  forward, move countries closer to achieving objectives of national poverty reduction strategies (the Millennium Development Goals, or MDGs), and ensure social and political stability by saving millions of lives and preventing life-long disabilities. Existing evidence provides us with clear guidance on what to invest in, how much to invest, and what can be achieved with this level of investment. This document brings this information together to present the case for Investing in Health for Africa: the case for strengthening systems for better health outcomes