More than 1 billion people—one-sixth of the world population—live in ecological hotspots, many of which are remote areas of critically important biodiversity under intense pressure from human activity. Biodiversity loss is a pressing global problem, with species extinctions happening at record levels. Threats to biodiversity include: population pressures from natural growth and human migration; unsustainable natural resource practices, such as slash-and-burn farming; ineffective governance structures and inadequate authority to protect local resources. Integrated Population, Health and Environment (PHE) programs acknowledge and address these threats, but do so with respect and understanding of the complex connections among human health, livelihoods and the environment upon which people living in these areas depend. The documents in this section describe the demographic, social and economic needs in remote, rural biodiversity areas and the associated threats to biodiversity.